Abortion

SPONTANEOUS ABORTIONS

Spontaneous abortions occur in about 15% of pregnancies and amongst these about 75% take place before 12 weeks. The risk of abortions increases with age of the mother, order of pregnancy and number of previous abortions. The causes of spontaneous abortions are many

  • Most early abortions are due to genetic defects. This may be due to delayed ovulation, faulty sperm formation, aging etc.
  • Maternal diseases: infections like rubella, Toxoplasmosis etc.
  • Injury, exposure to X-rays, chemicals.
  • Endocrinal: like progesterone and thyroid deficiency.
  • Malnutrition including deficiency of Vitamin E and folic acid
  • Anatomical defects like uterine anomalies; septate uterus are important causes of habitual abortions. Incompetent internal os ; lacerations of cervix; uterine fibroids may also lead to 2nd trimester abortions.
  • ABO blood group is important than due to Rh.

The examination of aborted material does not always give a clue as to cause and the possibility of multiple factors has to be kept in mind.

A woman will present with h/o bleeding PV after having missed her periods for some weeks; acute pain in lower abdomen and h/o products expelled.

Ultrasound can guide for further management. If it shows products remained inside uterus then check currette is necessary.

THREATENED ABORTION

There is history of Amenorrhoea, bleeding or spotting PV and pain in the abdomen but no products have been expelled.

Trans vaginal sonography gives us excellent result. It shows all the details presence of gestational sac, foetal pole, cardiac pulsation and placental condition. Here your doctor will try and save the pregnancy by conservative management of sedation and rest for at least 48 hours after bleeding stops. Inspite of it about 25% proceed to abortion.

INEVITABLE OR INCOMPLETE ABORTION

In the treatment of incomplete abortions; vacuum suction curettage is done and it has reduced the complications of excess bleeding and perforation of uterus.

HABITUAL ABORTION

When three or more consecutive abortions occur at about the same period of pregnancy it is termed as habitual abortion. About 1% of all abortions are habitual abortions. Amongst the general causes are diabetes, kidney disease, high BP and hypothyroidism, the local anatomical factors stated earlier and luteal or placental deficiencies have also to be considered.

Your doctor will mostly ask for Complete Blood picture, Haemoglobin estimation, blood group, blood sugar, VDRL test and urine routine & microscopic. In repeated abortions TORCH test is also advisable. Examination of vaginal smear for Karyopyknotic index, cervical mucous for fern pattern and HSG in some cases will also be useful.

Only in about 1/3 of the cases, cause is found and rectified. In others the treatment is mainly empirical with rest, vitamins, assurance and advice against strenuous exercise and sexual intercourse.

In certain cases of deficiency, progesterones orally or weekly injections are advised. The hormones are continued to about 36 weeks but at regular intervals clinical assessment is made of progressive uterine growth, amount of liquor and placental site. The concept of regular use of ultrasonography has changed the entire picture in management of habitual abortion.

When the cause is structural defect of the uterus like septate uterus and there is no other cause of habitual abortion, the surgical excision of septum is called for. In cases of cervical incompetence the famous Shirodkar's stitch is extremely useful. This is best done after 14th week of pregnancy. The suture is removed at 38 weeks or when the woman gets into labour. In cases of fibroids, fibroid removal is advised.

MISSED ABORTION

Missed abortion is one where inspite of abortion, the product of conception are not expelled and are retained in utero for two months or more after its death. The diagnosis may be made from the history: failure of uterus to grow when examined at adequate intervals and negative pregnancy test with urine or blood.

Regular use of ultrasound can clear the picture earlier. There is evidence of absence of heartbeats.

The treatment of early missed abortion is dilation and evacuation of products from the uterus. In late abortion whole foetus & placenta may be expelled out completely with use of extra amniotic injection of ethacrydine lactate. Nowadays with better concept or oral, local & injectable prostaglandins the procedure is somewhat smoother then before.

With advent of ultrasonography, use of 5000 IU hCG (human chorionic gonadotrophins) is continued till 12 weeks or 14 weeks of pregnancy and then patient can be given oral progesterones.

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